Through a global gene expression analysis (transcriptomic), the researchers were able to find and confirm a genetic signature common to these genodermatoses in patients’ cells. The profile targets cellular activation and alteration of the dermal microenvironment (lower layer of the skin) which could favour the progression of the disease, as well as skin cancer. Recessive dystrophic epidermolisis bullosa and the Kindler syndrome are diseases that cause fragility of the skin, caused by mutations in essential genes to attach the two layers of the skin. Patients with these diseases suffer from…
Read MoreAuthor: Tom Patriot
INLINE 6 vs. V6 – How it Works
Bella Hadid Responds to Body Shamers as Speculation About Thin Victoria’s Secret Models Grows
Bella Hadid officially confirmed that she’ll be walking in this year’s Victoria’s Secret Fashion Show by posting a series of sexy lingerie-clad shots from her fittings on Instagram. And the gallery has her followers divided on social media. Hadid posted five photos of herself modeling knee-high snakeskin boots, plus a black push-up bra and high-waisted underwear set, which showcased her slim figure and rib cage. And according to some commenters, they find her lingerie-clad photos “disturbing.” “Skin and bone. That second page is quite frankly disturbing,” one commenter wrote. “I have nothing against…
Read MoreSmoking and alcohol: Double trouble for the brain?
Along with many other harmful health consequences, smoking tobacco causes chemical changes, oxidative stress and inflammation in the brain. Excessive alcohol use can have similar effects. Surprisingly, however, very few studies have examined the combined impact of smoking and alcohol on the brain. Now, researchers reporting in ACS Chemical Neuroscience have shown that in rats, the joint use of tobacco and alcohol could increase neural damage in particular brain regions. According to the National Institute on Alcohol Abuse and Alcoholism, many people who smoke tobacco also drink alcohol excessively, and vice versa.…
Read MoreYo-yo dieting may increase women’s heart disease risk
Yo-yo dieting may make it harder for women to control a variety of heart disease risk factors, according to preliminary research presented at the American Heart Association’s Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2019, a premier global exchange of the latest advances in population-based cardiovascular science for researchers and clinicians. “Achieving a healthy weight is generally recommended as heart healthy but maintaining weight loss is difficult and fluctuations in weight may make it harder to achieve ideal cardiovascular health,” said Brooke Aggarwal, Ed.D., M.S., senior author…
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