New Culprit in Alzheimer’s Disease Development Identified

Findings may influence strategies for treatment. A recent study conducted at Nathan S. Kline Institute for Psychiatric Research (NKI) and NYU Langone Medical Center implicates a new culprit in Alzheimer’s disease development. The research reveals that ßCTF — the precursor of the amyloid beta (Aß) peptide — acts at the earliest stage of Alzheimer’s to initiate a range of abnormalities leading to the loss of groups of neurons critical for memory formation. Results from the study are published online July 21, 2015 in the journal, Molecular Psychiatry, and the article has…

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