Why the Ford Police Interceptor is the Ultimate Cop Car
Kate Middleton Jokes About Changing from High Heels to Combat Boots
Kate Middleton may be a duchess, but she’s not into wearing high heels 24/7. The fashionable royal has shown us that flats like knee-high boots and sneakers can be just as stylish (and functional) on the job, and yesterday was no exception. The Duchess of Cambridge ditched her ladylike wardrobe for a pair of industrial-chic combat boots from See by Chloé. Kate’s choice of footwear comes as no surprise, as yesterday’s agenda included a visit to the Scouts headquarters in London’s Gilwell Park. The trip, in which she learned about programs for young…
Read MoreWhen neurons are out of shape, antidepressants may not work
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD. Now, Salk Institute researchers have discovered differences in growth patterns of neurons of SSRI-resistant patients. The work, published in Molecular Psychiatry on March 22, 2019, has implications for depression as well as other psychiatric conditions such as bipolar disorder and schizophrenia that likely also involve abnormalities of the serotonin system in the brain. “With each new…
Read MoreDetrimental effect of overlooking female athletes’ nutritional needs
As poor nutrition can negatively affect everything from bone to reproductive health, more attention needs to be paid to the specific nutritional needs of female athletes, a collaborative study from New Zealand’s University of Otago and University of Waikato argues. Dr Katherine Black, of Otago’s Department of Human Nutrition, says most research into sport and nutrition focuses on male athletes, but the number of women participating in sport is growing, and female athletes have specific nutritional challenges and needs. “They are not just male athlete adjusted for weight,” she says.…
Read MoreNew one-two punch against melanoma in mouse model
Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system’s ability to fight melanoma in mice. The agents, dubbed s-DAB-IL-2 and s-DAB-IL-2(V6A), comprise a regulatory protein called human interleukin-2 fused to chemically modified portions of diphtheria toxin. In a mouse model of melanoma, the two agents, when given together, depleted so-called T regulatory cells that infiltrate tumors and hinder the immune system’s ability to…
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